Esau "Isaac" Wetherall was born in 1816 in Dinnington, London, England as the first child of James Wetherall and Mary Unknown. He died on 13 January 1889 in Toodyay, Western Australia, Australia. When he was 41, he married Mary "Malloney" Mellanby in February 1857 in Toodyay, Western Australia, Australia. When he was 48, he married Caroline Emily Minnor "Dowling" Golding on 30 May 1864 in Newcastle, Western Australia, Australia.

Esau "Isaac " Wetherall was also known as Isaac. Convict Number: Abt. 1850 (#54) Immigration: Arr.: 1 June 1850 (Per "Scindian")

Esau "Isaac" Wetherall and Mary "Malloney" Mellanby had the following children:

1. Sarah Wetherall was born in 1858. She died in 1874.
2. Mary Wetherall was born in July 1859. She died on Deceased. She married Donald Benedict Lee on 10 May 1877 in Newcastle, Western Australia, Australia.

Esau "Isaac" Wetherall and Caroline Emily Minnor "Dowling" Golding had no children.